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In this case, the updated vaccine includes an mRNA component of the original strain to provide an immune response that is broadly protective against COVID-19 and an mRNA component in common between the omicron variant BA.4 and BA.5 lineages to provide better protection against COVID-19 ...At this time, each participating CVS Pharmacy or MinuteClinic is offering either the Pfizer-BioNTech or the Moderna vaccine. Same-day or walk-in vaccination appointments may be possible but are subject to local demand. Schedule a COVID-19 vaccine or booster at CVS. Schedule a COVID-19 vaccine at MinuteClinic.Takeaway Bivalent COVID-19 vaccines contain two different components. One protects against the original strain of SARS-CoV-2, while the other protects against more recent variants. 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